Dosing & administration
BLENREP + Vd: Individualized dosing protocol
This treatment regimen involves the administration of BLENREP in combination with bortezomib and dexamethasone (BVd). BLENREP should be administered until disease progression or unacceptable toxicity.
Recommended starting dose schedule for BLENREP in the BVd triplet combination
| CYCLES 1-8 | CYCLE 9+ |
|---|---|
| BLENREP + Vd 2.5 mg/kg once every 3 weeks | BLENREP monotherapy 2.5 mg/kg once every 3 weeks until treatment completion |
Cycle length = 3 weeks
Adapted from the Product Monograph.
BLENREP + Pd: Individualized dosing protocol
This treatment regimen involves the administration of BLENREP in combination with pomalidomide and dexamethasone (BPd). BLENREP should be administered until disease progression or unacceptable toxicity.
Recommended starting dose schedule for BLENREP in the BPd triplet combination
| CYCLE 1 | CYCLE 2+ |
|---|---|
| BLENREP + Pd 2.5 mg/kg once | BLENREP + Pd 1.9 mg/kg once every 4 weeks until treatment completion |
Cycle length = 4 weeks
Adapted from the Product Monograph.